A kind of blood cell CMR, with a registration number of GBW(E)090065, has been developed. It is a...

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Development of Blood Cell CRMs

 

Blood cell certified reference materials (CRMs) form an effective carrier system in traceability of blood cell counting. The CRMs are widely used in blood cell analyzer calibration and verification. A kind of blood cell CMR, with a registration number of GBW(E)090065, has been developed, and it is an analog material very similar to human blood, which was prepared and synthesized by using special blood cells together with special save reagents.

 

Blood cell certified reference materials (CRMs) form an effective carrier system in blood cell counting traceability. The CRMs are widely used in blood cell analyzer calibration and verification.

 

A kind of blood cell CMR, with a registration number of GBW(E)090065, has been developed. It is an analog material very similar to human blood, which was prepared and synthesized by using special blood cells together with special save reagents. This developed CRM has four parameters, including counts of RBC, WBC, PLT and hematoglobin concentration. In determination of the RBC, WBC and PLT counting, microscope method with a counting chamber was used, whose accuracy was validated and the method deviation was decreased to less than 0.5% by some special means. Meanwhile, the counts of RBC, WBC and PLT were also measured using ICSH (international council for standardization in hematology) recommended reference methods, and it has got a very similar result to result using the microscope method.